Titre : | The chemical biology of nucleic acids |
Auteurs : | Mayer, Gunter, Auteur |
Type de document : | texte imprimé |
Editeur : | Chichester : Wiley, 2010 |
ISBN/ISSN/EAN : | 978-0-470-51974-5 |
Format : | 464 p. / ill. / 26 cm |
Note générale : | Bibliogr. , Index |
Langues: | Anglais |
Mots-clés: | Chimie des composés hétérocycliques ; Composés hétérocycliques Biochemistry ; Government Publication ; Heterocyclic compounds |
Résumé : | With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic–acid–templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non–coding RNA in |
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Code-barres | Cote | Support | Localisation | Section | Disponibilité |
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1.10195.00/1 | 1.10195.00 | Livre | A. Monographies | A. Ouvrages | Consultation sur place Exclu du prêt |